A model for decision support in signal triage.

  title={A model for decision support in signal triage.},
  author={Bennett S Levitan and Chuen L Yee and Leo J Russo and Richard Bayney and Adrian P Thomas and Stephen L Klincewicz},
  journal={Drug safety},
  volume={31 9},
Spontaneous reporting of suspected adverse drug reactions (ADRs) has long been a cornerstone of pharmacovigilance. With the increasingly large volume of ADRs, regulatory agencies, scientific/academic organizations and marketing authorization holders have applied statistical tools to assist in signal detection by identifying disproportionate reporting relationships in spontaneous reporting databases. These tools have generated large numbers of signals defined as drug-ADR reporting associations… CONTINUE READING

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