A mitochondrial DNA mutation influences the apoptotic effect of statins on prostate cancer.

Abstract

BACKGROUND Statins, 3-hydroxy-3 methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, are currently the most widely used cholesterol-lowering drugs. Previous epidemiological studies have suggested that there may be be an association between statin use and decreased risk of prostate cancer progression. Both inherited and somatic mutations of the… (More)
DOI: 10.1002/pros.23089

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Cite this paper

@article{Sun2015AMD, title={A mitochondrial DNA mutation influences the apoptotic effect of statins on prostate cancer.}, author={Qian Sun and Rebecca S. Arnold and Carrie Qi Sun and John A. Petros}, journal={The Prostate}, year={2015}, volume={75 16}, pages={1916-25} }