A mini-review: microRNA in arthritis.

@article{Nakasa2011AMM,
  title={A mini-review: microRNA in arthritis.},
  author={Tomoyuki Nakasa and Yoshihiko Nagata and Keiichiro Yamasaki and Mitsuo Ochi},
  journal={Physiological genomics},
  year={2011},
  volume={43 10},
  pages={
          566-70
        }
}
MicroRNA (miRNA) is a class of noncoding RNA that exhibits tissue- or developmental stage-specific expression patterns and negatively regulates gene expression. MiRNAs play an important role in human diseases, including osteoarthritis (OA) and rheumatoid arthritis (RA). OA is characterized by the progressive destruction of articular cartilage, and several miRNAs exhibit altered expression, playing a role in regulating gene expression in OA pathogenesis, especially in catabolic factors such as… CONTINUE READING

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