A middle-aged man presenting with unexplained mucosal erosions and progressive dyspnoea.

@article{Healy2015AMM,
  title={A middle-aged man presenting with unexplained mucosal erosions and progressive dyspnoea.},
  author={William Healy and Sara B. Peters and Serge Patrick Nana-Sinkam},
  journal={BMJ case reports},
  year={2015},
  volume={2015}
}
Paraneoplastic pemphigus (PNP) is a rare syndrome driven by antibodies (IgG) binding to desmogleins and other epidermal proteins leading to skin erosions. In rare instances, these same IgG proteins may also target the bronchial mucosa leading to an irreversible fibrotic reaction within the epithelium and subsequent obstructive lung disease. A 51-year-old man presented to the emergency department with 2-3-month history of dyspnoea as well as oral and genital ulcerations and inguinal… CONTINUE READING