A microtubule-binding myosin required for nuclear anchoring and spindle assembly

@article{Weber2004AMM,
  title={A microtubule-binding myosin required for nuclear anchoring and spindle assembly},
  author={Kari L. Weber and Anna Marie Sokac and Jonathan S. Berg and Richard E. Cheney and William M. Bement},
  journal={Nature},
  year={2004},
  volume={431},
  pages={325-329}
}
Proper spindle positioning and orientation are essential for asymmetric cell division and require microtubule–actin filament (F-actin) interactions in many systems. Such interactions are particularly important in meiosis, where they mediate nuclear anchoring, as well as meiotic spindle assembly and rotation, two processes required for asymmetric cell division. Myosin-10 proteins are phosphoinositide-binding, actin-based motors that contain carboxy-terminal MyTH4 and FERM domains of unknown… 

Myosin-10 and actin filaments are essential for mitotic spindle function

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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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LIM Kinase-mediated Cofilin Phosphorylation during Mitosis Is Required for Precise Spindle Positioning*

TLDR
It is shown that mitotic LIMK1 activation is critical for accurate spindle orientation in mammalian cells and suggested that LIMK 1-mediated cofilin phosphorylation is required for accurateSpindle orientation by stabilizing cortical actin networks during mitosis.
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