A microspectrophotometric method for the determination of cytochrome oxidase.

@article{Cooperstein1951AMM,
  title={A microspectrophotometric method for the determination of cytochrome oxidase.},
  author={S J Cooperstein and Arnold Lazarow},
  journal={The Journal of biological chemistry},
  year={1951},
  volume={189 2},
  pages={665-70}
}
The method used by Potter, Albaum, and others (1, 2) for studying the effects of various inhibitors on cytochrome oxidase has been adapted successfully to the assay of the cytochrome oxidase content of rat tissues. The rate of enzymatic oxidation of reduced cytochrome c is measured. A microadaptation enables the measurement of the cytochrome oxidase content of as little as 4 y (wet weight) of an active tissue such as heart.