A microfiltration bioreactor to achieve high cell density in Sulfolobus solfataricus fermentation

@article{Schiraldi1999AMB,
  title={A microfiltration bioreactor to achieve high cell density in Sulfolobus solfataricus fermentation},
  author={Chiara Schiraldi and Francesco Marulli and Isabella Di Lernia and Angela Martino and Mario Rosa},
  journal={Extremophiles},
  year={1999},
  volume={3},
  pages={199-204}
}
A novel technique is proposed to achieve higher cell yield in extremophile fermentation. Because the accumulation of toxic compounds is thought to be responsible for low biomass yields, a bioreactor has been designed based on a microfiltration hollow-fiber module located inside the traditional fermentation vessel. Using the cul-tivation of the thermoacidophilic archeon Sulfolobus solfataricus Gı as a model, a biomass of 35 g l−1 dry weight was obtained which proved greater than that of 2 g l−1… CONTINUE READING
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