A microRNA regulatory mechanism of osteoblast differentiation.

@article{Inose2009AMR,
  title={A microRNA regulatory mechanism of osteoblast differentiation.},
  author={Hiroyuki Inose and Hiroki Ochi and Ayako Kimura and Koji Fujita and Ren Xu and Shingo Sato and Makiko Iwasaki and Satoko Sunamura and Yasuhiro Takeuchi and Seiji Fukumoto and Kuniaki Saito and Takashi Nakamura and Haruhiko Siomi and Hiroshi Ito and Yoshiyasu Arai and Ken-ichi Shinomiya and Shu Takeda},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2009},
  volume={106 49},
  pages={20794-9}
}
Growing evidence shows that microRNAs (miRNAs) regulate various developmental and homeostatic events in vertebrates and invertebrates. Osteoblast differentiation is a key step in proper skeletal development and acquisition of bone mass; however, the physiological role of non-coding small RNAs, especially miRNAs, in osteoblast differentiation remains elusive. Here, through comprehensive analysis of miRNAs expression during osteoblast differentiation, we show that miR-206, previously viewed as a… CONTINUE READING

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