A microRNA profile comparison between thoracic aortic dissection and normal thoracic aorta indicates the potential role of microRNAs in contributing to thoracic aortic dissection pathogenesis.

@article{Liao2011AMP,
  title={A microRNA profile comparison between thoracic aortic dissection and normal thoracic aorta indicates the potential role of microRNAs in contributing to thoracic aortic dissection pathogenesis.},
  author={Mingfang Liao and Sili Zou and Jianfeng Weng and Lewei Hou and Lin Yang and Zhiqing Zhao and Junmin Bao and Zaiping Jing},
  journal={Journal of vascular surgery},
  year={2011},
  volume={53 5},
  pages={1341-1349.e3}
}
OBJECTIVES Our aim was to identify important microRNAs (miRNAs) that might play an important role in contributing to aortic dissection by conducting a miRNA profile comparison between thoracic aortic dissection (TAD) and normal thoracic aorta. METHODS The differentially expressed miRNA profiles of the aortic tissue between TAD patients (n = 6) and age-matched donors without aortic diseases (NA; n = 6) were analyzed by miRNA microarray. Quantitative reverse transcription polymerase chain… CONTINUE READING
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