A methylated Neurospora 5S rRNA pseudogene contains a transposable element inactivated by repeat-induced point mutation.

@article{Margolin1998AMN,
  title={A methylated Neurospora 5S rRNA pseudogene contains a transposable element inactivated by repeat-induced point mutation.},
  author={Brian S. Margolin and Philip W. Garrett-Engele and James Stevens and Dominik Fritz and Carrie M. Garrett-Engele and Robert L. Metzenberg and Eric U Selker},
  journal={Genetics},
  year={1998},
  volume={149 4},
  pages={1787-97}
}
In an analysis of 22 of the roughly 100 dispersed 5S rRNA genes in Neurospora crassa, a methylated 5S rRNA pseudogene, Psi63, was identified. We characterized the Psi63 region to better understand the control and function of DNA methylation. The 120-bp 5S rRNA-like region of Psi63 is interrupted by a 1.9-kb insertion that has characteristics of sequences that have been modified by repeat-induced point mutation (RIP). We found sequences related to this insertion in wild-type strains of N. crassa… CONTINUE READING
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