A methodology for testing for statistically significant differences between fully 3D PET reconstruction algorithms.

@article{Furuie1994AMF,
  title={A methodology for testing for statistically significant differences between fully 3D PET reconstruction algorithms.},
  author={Sergio Shiguemi Furuie and Gabor T. Herman and T. K. Narayan and Paul E. Kinahan and Joel S. Karp and Robert M. Lewitt and Samuel Matej},
  journal={Physics in medicine and biology},
  year={1994},
  volume={39 3},
  pages={
          341-54
        }
}
We present a practical methodology for evaluating 3D PET reconstruction methods. It includes generation of random samples from a statistically described ensemble of 3D images resembling those to which PET would be applied in a medical situation, generation of corresponding projection data with noise and detector point spread function simulating those of a 3D PET scanner, assignment of figures of merit appropriate for the intended medical applications, optimization of the reconstruction… CONTINUE READING
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