A methodology for generating normal and pathological brain perfusion SPECT images for evaluation of MRI/SPECT fusion methods: application in epilepsy.

@article{Grova2003AMF,
  title={A methodology for generating normal and pathological brain perfusion SPECT images for evaluation of MRI/SPECT fusion methods: application in epilepsy.},
  author={Christophe Grova and Pierre Jannin and Arnaud Biraben and Ir{\`e}ne Buvat and Habib Benali and Aline M Bernard and J. M. Scarabin and Bernard Gibaud},
  journal={Physics in medicine and biology},
  year={2003},
  volume={48 24},
  pages={4023-43}
}
Quantitative evaluation of brain MRI/SPECT fusion methods for normal and in particular pathological datasets is difficult, due to the frequent lack of relevant ground truth. We propose a methodology to generate MRI and SPECT datasets dedicated to the evaluation of MRI/SPECT fusion methods and illustrate the method when dealing with ictal SPECT. The method consists in generating normal or pathological SPECT data perfectly aligned with a high-resolution 3D T1-weighted MRI using realistic Monte… CONTINUE READING