A method of resolution improvement by the measurement of cell membrane capacitance.

@article{Rech1996AMO,
  title={A method of resolution improvement by the measurement of cell membrane capacitance.},
  author={Francesca Rech and V. Rohlicek and Andrew Schmid},
  journal={Physiological research},
  year={1996},
  volume={45 5},
  pages={
          421-5
        }
}
When measuring cell membrane electrical capacitance in whole cell configuration using alternating currents, the resolution decreases with increasing membrane conductance and pipette resistance. Improved resolution was attained by the dual-frequency method which was modified as to control the voltage amplitude of one of the measuring frequencies. A model circuit was developed for the verification of the method. This circuit allows measurement of calibrated capacitance changes even in the range… CONTINUE READING

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