A method of inducing global cerebral ischemia.


The four-vessel occlusion (4-VO) method of global forebrain cerebral ischemia mimics the human clinical condition of cardiac arrest. It results in selective neuronal damage and is a useful experimental system to dissect underlying mechanisms behind ischemic phenomena such as the differential susceptibility of CA1 compared to the CA3 region of the… (More)
DOI: 10.1007/978-1-4939-0320-7_10


Cite this paper

@article{Hadley2014AMO, title={A method of inducing global cerebral ischemia.}, author={Gina Hadley and Michalis Papadakis and Alastair M Buchan}, journal={Methods in molecular biology}, year={2014}, volume={1135}, pages={111-20} }