A method for removal of global effects from fMRI time series

@article{Macey2004AMF,
  title={A method for removal of global effects from fMRI time series},
  author={Paul M Macey and Katherine E. Macey and Rajesh Kumar and Ronald M. Harper},
  journal={NeuroImage},
  year={2004},
  volume={22},
  pages={360-366}
}
We present a technique for removing global effects from functional magnetic resonance imaging (fMRI) images, using a voxel-level linear model of the global signal (LMGS). The procedure does not assume low-frequency global effects and is based on the assumption that the global signal (the time course of the average intensity per volume) is replicated in the same pattern throughout the brain, although not necessarily at the same magnitude. A second assumption is that all effects that match the… CONTINUE READING
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