A method for pre-operative single-subject thalamic segmentation based on probabilistic tractography for essential tremor deep brain stimulation

@article{Middlebrooks2017AMF,
  title={A method for pre-operative single-subject thalamic segmentation based on probabilistic tractography for essential tremor deep brain stimulation},
  author={E H Middlebrooks and Vanessa Milanezi Holanda and I S Tuna and Hrishikesh D. Deshpande and Markus Bredel and Leonardo Almeida and Harrison Walker and Barton L. Guthrie and Kelly Foote and Michael S. Okun},
  journal={Neuroradiology},
  year={2017},
  volume={60},
  pages={303-309}
}
PurposeDeep brain stimulation is a common treatment for medication-refractory essential tremor. Current coordinate-based targeting methods result in variable outcomes due to variation in thalamic structure and the optimal patient-specific functional location. The purpose of this study was to compare the coordinate-based pre-operative targets to patient-specific thalamic segmentation utilizing a probabilistic tractography methodology.MethodsUsing available diffusion MRI of 32 subjects from the… CONTINUE READING
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