A method for intracochlear drug delivery in the mouse

@article{Chen2006AMF,
  title={A method for intracochlear drug delivery in the mouse},
  author={Zhiqiang Chen and Anthony Alan Mikulec and Michael J McKenna and William F. Sewell and Sharon Guilds. Kujawa},
  journal={Journal of Neuroscience Methods},
  year={2006},
  volume={150},
  pages={67-73}
}
The confluence of two rapidly emerging research arenas - development of mouse models of human deafness and inner ear drug therapy for treatment and prevention of hearing loss - provides an opportunity for unprecedented approaches to study and treat deafness. Toward such goals, we have developed a method for intracochlear drug delivery in the mouse. The bulla was exposed using a ventral approach and the stapedial artery cauterized. An opening made into the inferior-medial aspect of the bulla… CONTINUE READING
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