A method for finding single-nucleotide polymorphisms with allele frequencies in sequences of deep coverage

@article{Wang2005AMF,
  title={A method for finding single-nucleotide polymorphisms with allele frequencies in sequences of deep coverage},
  author={Jianmin Wang and Xiaoqiu Huang},
  journal={BMC Bioinformatics},
  year={2005},
  volume={6},
  pages={220 - 220}
}
The allele frequencies of single-nucleotide polymorphisms (SNPs) are needed to select an optimal subset of common SNPs for use in association studies. Sequence-based methods for finding SNPs with allele frequencies may need to handle thousands of sequences from the same genome location (sequences of deep coverage). We describe a computational method for finding common SNPs with allele frequencies in single-pass sequences of deep coverage. The method enhances a widely used program named… CONTINUE READING
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