A method for developing high-density SNP maps and its application at the type 1 angiotensin II receptor (AGTR1) locus.

@article{Antonellis2002AMF,
  title={A method for developing high-density SNP maps and its application at the type 1 angiotensin II receptor (AGTR1) locus.},
  author={Anthony Antonellis and John J. Rogus and Luis Henrique Santos Canani and Yuchiro Makita and Marcus G. Pezzolesi and Moon Suk Nam and Daniel Jun Xian Ng and Dariusz K Moczulski and James H. Warram and Andrzej S Krolewski},
  journal={Genomics},
  year={2002},
  volume={79 3},
  pages={326-32}
}
Evaluating the potential genetic components of complex disease will likely be aided through the use of dense polymorphism maps. Previously, we reported evidence for linkage with diabetic nephropathy on chromosome 3q in a region encompassing the type 1 angiotensin II receptor (AGTR1) gene. To further investigate any role for this gene in disease onset, we set out to design a dense polymorphism map spanning the AGTR1 locus for the purpose of association studies. Toward this goal, we have… CONTINUE READING

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