A metalloprotease-disintegrin participating in myoblast fusion


SKELETAL muscle development involves the formation of multi-nucleated myotubes. This is thought to proceed by the induction of differentiation (acquisition of fusion competence) of myoblast cells, their aggregation, and union of their plasma membranes1á¤-3. Various membrane proteins including N-4,5 and M-cadherins6, N-5,7-9 and V-CAMs10 and integrins10,11… (More)
DOI: 10.1038/377652a0


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