A metalloprotease-disintegrin participating in myoblast fusion

@article{YagamiHiromasa1995AMP,
  title={A metalloprotease-disintegrin participating in myoblast fusion},
  author={Takako Yagami-Hiromasa and Tomomi Sato and Tomohiro Kurisaki and Keiju Kamijo and Yo-ichi Nabeshima and Atsuko Fujisawa-Sehara},
  journal={Nature},
  year={1995},
  volume={377},
  pages={652-656}
}
  • Takako Yagami-Hiromasa, Tomomi Sato, +3 authors Atsuko Fujisawa-Sehara
  • Published 1995
  • Medicine, Biology
  • Nature
  • SKELETAL muscle development involves the formation of multi-nucleated myotubes. This is thought to proceed by the induction of differentiation (acquisition of fusion competence) of myoblast cells, their aggregation, and union of their plasma membranes1á¤-3. Various membrane proteins including N-4,5 and M-cadherins6, N-5,7-9 and V-CAMs10 and integrins10,11 participate in myotube formation, but the molecular mechanisms of muscle cell fusion are poorly understood. Here we report the identification… CONTINUE READING

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