A metabotropic glutamate receptor family gene in Dictyostelium discoideum.

@article{Taniura2006AMG,
  title={A metabotropic glutamate receptor family gene in Dictyostelium discoideum.},
  author={Hideo Taniura and Noriko Sanada and Nobuyuki Kuramoto and Yukio Yoneda},
  journal={The Journal of biological chemistry},
  year={2006},
  volume={281 18},
  pages={12336-43}
}
Metabotropic glutamate receptors (mGluRs) are a class of G-protein-coupled receptors that possess a seven transmembrane region involved in the modulation of excitatory synaptic transmission in the nervous system. mGluR orthologs have been identified in Drosophila, Caenorhabditis elegans, and higher organisms. Drosophila possesses two mGluR genes, DmGluRA and DmXR. We screened the Dictyostelium genome data base using the ligand binding domain of rat mGluR1 as bait, and identified a new receptor… CONTINUE READING