A metabolomics investigation of the function of the ESX-1 gene cluster in mycobacteria.

Abstract

The ESX-1 gene cluster, encoding the Type-VII secretion (T7S) system and its virulence associated proteins, ESAT-6 and CFP-10, is thought to be responsible for the transport of extracellular proteins across the hydrophobic and highly impermeable, cell envelope of Mycobacterium, and is involved in virulence in Mycobacterium tuberculosis, the causative agent… (More)
DOI: 10.1016/j.micpath.2016.10.008

Cite this paper

@article{Loots2016AMI, title={A metabolomics investigation of the function of the ESX-1 gene cluster in mycobacteria.}, author={Du Toit Loots and Conrad C Swanepoel and Mae Newton-Foot and Nicolaas C Gey van Pittius}, journal={Microbial pathogenesis}, year={2016}, volume={100}, pages={268-275} }