A meta-analysis on the efficacy and safety of St John’s wort extract in depression therapy in comparison with selective serotonin reuptake inhibitors in adults

  title={A meta-analysis on the efficacy and safety of St John’s wort extract in depression therapy in comparison with selective serotonin reuptake inhibitors in adults},
  author={Yonghua Cui and Yi Zheng},
  journal={Neuropsychiatric Disease and Treatment},
  pages={1715 - 1723}
Objective The aim of the study was to investigate the efficacy and safety of St John’s wort extract and selective serotonin reuptake inhibitors (SSRIs) in the treatment of depression. Methods Databases were searched for studies comparing efficacy and/or safety of St John’s wort extract with SSRIs in depression from 1966 to April 2015. Stata software was used for statistical analysis. Results Twenty-seven studies met the study entry criteria. A total of 3,126 patients with depression were… 

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