A meta-analysis of the role of smoking in inflammatory bowel disease

@article{Calkins1989AMO,
  title={A meta-analysis of the role of smoking in inflammatory bowel disease},
  author={Beverly M. Calkins},
  journal={Digestive Diseases and Sciences},
  year={1989},
  volume={34},
  pages={1841-1854}
}
  • B. Calkins
  • Published 1989
  • Medicine
  • Digestive Diseases and Sciences
A relationship between not smoking and ulcerative colitis has been examined in all English reports. This paper evaluates the ulcerative colitis/nonsmoking and the Crohn's disease/smoking association by meta-analysis and against causality criterion for chronic diseases. A review of the literature, meta-analysis of selected studies, and assessment of causality criterion all suggest that not smoking and ulcerative colitis and smoking and Crohn's disease are consistent with a causal relationship… Expand
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610 Citations
Highly Influential Citations
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Background Citations
171
Methods Citations
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Results Citations
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610 Citations

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Citation Type

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Epidemiological evidence suggests that ulcerative colitis is a disease ofnonsmokers, while Crohn's disease is a disease of smokers. The relative risk of developing ulcerative colitis is not only… Expand
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References

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TLDR
The association between current smoking and Crohn's disease was even stronger when age at first onset of bowel symptoms was considered as the index date, but the risk for ex-smokers fell below unity. Expand
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