A meta-analysis of the role of smoking in inflammatory bowel disease

@article{Calkins1989AMO,
  title={A meta-analysis of the role of smoking in inflammatory bowel disease},
  author={Beverly M. Calkins},
  journal={Digestive Diseases and Sciences},
  year={1989},
  volume={34},
  pages={1841-1854}
}
  • B. Calkins
  • Published 1 December 1989
  • Medicine
  • Digestive Diseases and Sciences
A relationship between not smoking and ulcerative colitis has been examined in all English reports. This paper evaluates the ulcerative colitis/nonsmoking and the Crohn's disease/smoking association by meta-analysis and against causality criterion for chronic diseases. A review of the literature, meta-analysis of selected studies, and assessment of causality criterion all suggest that not smoking and ulcerative colitis and smoking and Crohn's disease are consistent with a causal relationship… 
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605 Citations
Highly Influential Citations
26
Background Citations
172
Methods Citations
7
Results Citations
8

605 Citations

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References

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TLDR
The association between current smoking and Crohn's disease was even stronger when age at first onset of bowel symptoms was considered as the index date, but the risk for ex-smokers fell below unity.
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TLDR
Patients with ISS and ulcerative colitis smoked significantly less than those with Crohn's disease and any protective role postulated for smoking in the patho­ genesis of ulceratives colitis should also be considered for 18S.
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TLDR
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