A meta-analysis of the association between DRD4 polymorphism and novelty seeking

@article{Kluger2002AMO,
  title={A meta-analysis of the association between DRD4 polymorphism and novelty seeking},
  author={Avraham N. Kluger and Zehava Siegfried and Richard P. Ebstein},
  journal={Molecular Psychiatry},
  year={2002},
  volume={7},
  pages={712-717}
}
A meta-analytical review of 20 studies (n = 3907) of the association between DRD4 polymorphism and novelty seeking suggests the following conclusions: (a) on average, there is no association between DRD4 polymorphism and novelty seeking (average d= 0.06 with 95% CI of ± 0.09), where 13 reports suggest that the presence of longer alleles is associated with higher novelty seeking scores and seven reports suggest the opposite; (b) there is a true heterogeneity among the studies (ie, unknown… CONTINUE READING