• DOI:10.1016/j.neubiorev.2006.03.004
Corpus ID: 15511760

A meta-analysis of structural brain abnormalities in PTSD

@article{Karl2006AMO,
  title={A meta-analysis of structural brain abnormalities in PTSD},
  author={A. Karl and M. Schaefer and L. Malta and Denise D{\"o}rfel and A. Werner},
  journal={Neuroscience & Biobehavioral Reviews},
  year={2006},
  volume={30},
  pages={1004-1031}
}

• A. Karl, M. Schaefer, +2 authors A. Werner
• Published 2006
• Psychology, Medicine
• Neuroscience & Biobehavioral Reviews

This series of meta-analyses examined structural abnormalities of the hippocampus and other brain regions in persons with PTSD compared to trauma-exposed and non-exposed control groups. The findings were significantly smaller hippocampal volumes in persons with PTSD compared to controls with and without trauma exposure, but group differences were moderated by MRI methodology, PTSD severity, medication, age and gender. Trauma-exposed persons without PTSD also showed significantly smaller… Expand

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