A meta-analysis of six-month studies of antiplaque and antigingivitis agents.

@article{Gunsolley2006AMO,
  title={A meta-analysis of six-month studies of antiplaque and antigingivitis agents.},
  author={John C. Gunsolley},
  journal={Journal of the American Dental Association},
  year={2006},
  volume={137 12},
  pages={
          1649-57
        }
}
  • J. Gunsolley
  • Published 1 December 2006
  • Medicine
  • Journal of the American Dental Association
BACKGROUND AND METHODS The author conducted a systematic review of the literature to evaluate the efficacy of antigingivitis and antiplaque products in six-month trials. He searched electronic databases for six-month randomized clinical studies that evaluated both antiplaque and antigingivitis properties of dentifrices or mouthrinses. In addition, the author solicited unpublished studies from manufacturers. RESULTS Seventeen studies support the antiplaque, antigingivitis effects of… 

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References

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Comparative antiplaque and antigingivitis effectiveness of a chlorhexidine and an essential oil mouthrinse: 6-month clinical trial.
TLDR
This 6-month controlled clinical study demonstrated that the essential oil Mouthrinse and the chlorhexidine mouthrinse had comparable antiplaque and antigingivitis activity.
Comparative efficacy of an antiseptic mouthrinse and an antiplaque/antigingivitis dentifrice. A six-month clinical trial.
TLDR
Clinicians should consider Listerine Antiseptic, in conjunction with usual oral hygiene, if more rigorous plaque control is desired, when considering an antiplaque/antigingivitis product to recommend to patients.
A clinical methods study of the effects of triclosan dentifrices on gingivitis over six months.
TLDR
It is suggested that a study design which includes subjects with more severe gingivitis at baseline has the required sensitivity to demonstrate treatment benefits for triclosan dentifrices.
Clinical effect of a triclosan-containing dentifrice on plaque and gingivitis: a six-month study.
TLDR
It was concluded that the twice-daily use of the triclosan-containing dentifrice resulted in significant reduction in supragingival plaque formation and a significant improvement in gingival health without the presence of any extrinsic staining or objectionable taste.
The effect of three commercially available dentifrices containing triclosan on supragingival plaque formation and gingivitis: a six month clinical study.
TLDR
The subjects using the commercially available triclosan/copolymer dentifrice had, after six months, statistically significant reductions in supragingival plaque, plaque severity, and gingivitis severity, as compared to the placebo dentif Rice.
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TLDR
The results support previous published results on the superiority of 0.12% chlorhexidine when used in conjunction with professional care and as an adjunct to routine oral hygiene practices.
Six-month study of the effects of a chlorhexidine mouthrinse on gingivitis in adults
TLDR
It was concluded that a 0.12% chlorhexidine gluconate mouthrinse can provide an important adjunct to the prevention and control of gingivitis when used with regular personal oral hygiene procedures and professional care.
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TLDR
It can be concluded from this clinical study that the twice daily use of the dentifrice containing 0.3% Triclosan and 2.0% of a copolymer in a 0.243% sodium fluoride/silica base provides statistically significant reductions in both supragingival plaque formation and gingivitis.
Effect of a dentifrice containing triclosan and a copolymer on plaque formation and gingivitis.
TLDR
It can be concluded from this clinical study that the twice daily use of the dentifrice containing 0.3% Triclosan and 2.0% of a copolymer in a 0.243% sodium fluoride/silica base provides statistically significant reductions in both supragingival plaque formation and gingivitis.
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TLDR
It was concluded that the twice daily use of a dentifrice containing 0.3% triclosan and 2% of a copolymer reduces supragingival plaque deposit formation and gingivitis to a highly significant degree, without any extrinsic stains observed.
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