A meta-analysis of six-month studies of antiplaque and antigingivitis agents.

@article{Gunsolley2006AMO,
  title={A meta-analysis of six-month studies of antiplaque and antigingivitis agents.},
  author={John C. Gunsolley},
  journal={Journal of the American Dental Association},
  year={2006},
  volume={137 12},
  pages={
          1649-57
        }
}
  • J. Gunsolley
  • Published 1 December 2006
  • Medicine
  • Journal of the American Dental Association
BACKGROUND AND METHODS The author conducted a systematic review of the literature to evaluate the efficacy of antigingivitis and antiplaque products in six-month trials. He searched electronic databases for six-month randomized clinical studies that evaluated both antiplaque and antigingivitis properties of dentifrices or mouthrinses. In addition, the author solicited unpublished studies from manufacturers. RESULTS Seventeen studies support the antiplaque, antigingivitis effects of… Expand
Clinical efficacy of antimicrobial mouthrinses.
TLDR
The results suggest that the clinical benefits of anti-plaque, anti-gingivitis mouthrinses are similar to the benefits of oral prophylaxis and oral hygiene instructions at six month recall appointments. Expand
Comparative antiplaque and antigingivitis efficacy of a multipurpose essential oil-containing mouthrinse and a cetylpyridinium chloride-containing mouthrinse: A 6-month randomized clinical trial.
TLDR
These findings support the regular long-term use of the EO mouthrinse and selection over a 0.05% CPC rinse for better efficacy and demonstrate increasing plaque and gingivitis reductions over 6 months. Expand
Comparative antiplaque and antigingivitis efficacy of three antiseptic mouthrinses: a two week randomized clinical trial.
TLDR
In conclusion, the EO mouthrinse demonstrated significantly greater antiplaque and antigingivitis efficacy than both CPC-containing mouthrinses and the negative control. Expand
The effect of cetylpyridinium chloride mouthrinse as adjunct to toothbrushing compared to placebo on interproximal plaque and gingival inflammation—a systematic review with meta-analyses
TLDR
When considering interproximal surfaces, CPC is efficacious both in plaque and gingival inflammatory parameters, demonstrating the potential to compensate for the limitations of inter Proximal plaque control. Expand
Meta-analysis of the effect of an essential oil-containing mouthrinse on gingivitis and plaque.
TLDR
This is the first meta-analysis to demonstrate the clinically significant, site-specific benefit of adjunctive EO treatment in people within a 6-month period (that is, between dental visits). Expand
Antiplaque and antigingivitis efficacy of an alcohol-free essential-oil containing mouthrinse: a 2-week clinical trial.
TLDR
Alcohol-free essential oils containing mouthrinse (LZ) was more effective than C in reducing plaque and gingivitis and the mean Turesky Modification of the Quigley-Hein Plaque Index (PI) at 2 weeks were the primary efficacy endpoints. Expand
Mouthrinses and dentifrices are effective antigingivitis and antiplaque agents.
  • R. Garcia
  • Medicine
  • The journal of evidence-based dental practice
  • 2008
TLDR
Evaluate the efficacy of dentifrices and mouthrinses as antigingivitis and antiplaque agents in adults and systematic review of 6-Month RCTs that evaluated both the Antiplaque and Antigingvitis Properties of Dentifrices or Mouth Rinses in Adults found them to be effective. Expand
Uncontrolled randomized clinical trial demonstrates similar long-term (6 months) antigingivitis and antiplaque efficacy for 2 mouth rinses: one that uses cetylpyridinium chloride (CPC) as an active agent and the other that uses essential oils (EO) as an active agent.
  • J. Gunsolley
  • Medicine
  • The journal of evidence-based dental practice
  • 2008
TLDR
The purpose of this study was to compare the long-term clinical and microbiological effects of an experimental CPC mouth rinse with that of a commercially available and widely used EO mouth rinse in an unsupervised, uncontrolled 6-month randomized clinical trial. Expand
Efficacy of adjunctive anti-plaque chemical agents: a systematic review and network meta-analyses of the Turesky modification of the Quigley and Hein plaque index.
TLDR
Dentifrices containing triclosan-copolymer or chlor hexidine and mouthrinses containing essential oils or chlorhexidine showed the greatest effect on PlI scores as assessed with NMA, within the limitations of this study. Expand
Antiplaque and antigingivitis efficacy of cetylpyridinium chloride with zinc lactate compared with essential oil mouthrinses: Randomized clinical trial.
TLDR
The regimen including a mouthrinse containing CPC + Zn + F presented higher antiplaque and antigingivitis effects than EO and control regimens, and was an effective protocol for the control of dental plaque and gingIVitis. Expand
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It can be concluded from this clinical study that the twice daily use of the dentifrice containing 0.3% Triclosan and 2.0% of a copolymer in a 0.243% sodium fluoride/silica base provides statistically significant reductions in both supragingival plaque formation and gingivitis. Expand
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