A meta-analysis of pregnancy outcomes in women with polycystic ovary syndrome.

@article{Boomsma2006AMO,
  title={A meta-analysis of pregnancy outcomes in women with polycystic ovary syndrome.},
  author={Carolien M. Boomsma and Marinus J. C. Eijkemans and Edward G. Hughes and Gerard H. A. Visser and Bart C. J. M. Fauser and Nicholas S. Macklon},
  journal={Human reproduction update},
  year={2006},
  volume={12 6},
  pages={
          673-83
        }
}
Polycystic ovary syndrome (PCOS) is a common reproductive disorder associated with many characteristic features, including hyperandrogenaemia, insulin resistance and obesity which may have significant implications for pregnancy outcomes and long-term health of the woman. This meta-analysis was conducted to evaluate the risk of pregnancy and neonatal complications in women with PCOS. Electronic databases were searched for the following MeSH headings: PCOS, hyperandrogenism, pregnancy outcome… 
Obstetric complications in women with polycystic ovary syndrome: a systematic review and meta-analysis
TLDR
Women with PCOS have increased risk of adverse pregnancy and neonatal complications and it is necessary to establish guidelines for supervision during pregnancy and parturition to prevent these complications.
Association between polycystic ovary syndrome and the risk of pregnancy complications
TLDR
Overall, PCOS in pregnancy was associated with greater risk of GDM, preeclampsia, PIH, preterm delivery, cesarean delivery, miscarriage, hypoglycemia, and perinatal death, and subgroup analysis suggested that these associations might be influenced by study design and pre-BMI.
A meta-analysis of pregnancy-related outcomes and complications in women with polycystic ovary syndrome undergoing IVF.
TLDR
Evidence is provided to support the observation that despite the fact that PCOS patients achieve a better live birth rate, physicians should continue to consider them to be at high risk of adverse pregnancy-related outcomes.
Efficacy of metformin on pregnancy complications in women with polycystic ovary syndrome: a meta-analysis
TLDR
Metformin therapy throughout pregnancy can reduce the RR of miscarriage and premature birth incidence in PCOS patients with no serious side effects.
Risk of gestational diabetes mellitus in women with polycystic ovary syndrome: a systematic review and a meta-analysis.
TLDR
Significant heterogeneity among studies and dependence of the outcome on study type make the higher risk of GDM in women with PCOS a questionable finding.
Pregnancy complications in women with polycystic ovary syndrome.
TLDR
The strategies for prevention and management of pregnancy complications in women with PCOS, and whether long-term health of these women is influenced, and to what extent, by pregnancy and/or pregnancy complications, remain to be elucidated are summarized.
Pregnancy complications in infertile patients with polycystic ovary syndrome: updated evidence.
TLDR
Evidence-based data regarding the pregnancy complications in infertile patients with PCOS is evaluated and any interventions to reduce the risk of obstetric and neonatal risks in women affected by PCOS and in their offspring are identified.
Maternal polycystic ovary syndrome may be associated with adverse pregnancy outcomes.
TLDR
Women affected by PCOS carry an increased risk of adverse pregnancy outcomes, and the higher occurrence of adverse outcomes may be, at least partly, related to a higher weight gain during pregnancy in PCOS group with respect to the other groups.
Pregnancy complications in women with polycystic ovary syndrome.
TLDR
Pregnant women with PCOS experience a higher incidence of perinatal morbidity from gestational diabetes, pregnancy-induced hypertension, and preeclampsia, and their babies are at an increased risk of neonatal complications, such as preterm birth and admission at a neonatal intensive care unit.
Pregnancy outcomes and the effect of metformin treatment in women with polycystic ovary syndrome: an overview
TLDR
Pregnant women with PCOS are at an increased risk of developing gestational diabetes, hypertensive disorders of pregnancy, preterm birth and early pregnancy loss, and whether metformin should be administered throughout pregnancy still remains controversial.
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References

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TLDR
It is concluded that PCOS slightly increases the risk for GDM, but does not have an important effect on the rate of premature delivery and pre-eclampsia.
Impact of Insulin Resistance on Pregnancy Complications and Outcome in Women with Polycystic Ovary Syndrome
TLDR
The frequencies of pre-eclampsia and GDM are increased in PCOS pregnancies, and insulin resistance prior to pregnancy did not further increase the frequency of GDM.
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TLDR
An increased cancellation rate, but more oocytes retrieved per retrieval and a lower fertilization rate in PCOS undergoing IVF is demonstrated, while PCOS and control patients achieved similar pregnancy and live birth rates per cycle.
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TLDR
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TLDR
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TLDR
Whether women with polycystic ovary syndrome (PCOS) are more likely to develop gestational diabetes mellitus compared with age- and weight-matched controls is investigated to determine.
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TLDR
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TLDR
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TLDR
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