A meta-analysis and systematic review of the efficacy and safety of anticoagulants as cancer treatment: impact on survival and bleeding complications.

@article{Kuderer2007AMA,
  title={A meta-analysis and systematic review of the efficacy and safety of anticoagulants as cancer treatment: impact on survival and bleeding complications.},
  author={Nicole M. Kuderer and Alok A Khorana and Gary H. Lyman and Charles W. Francis},
  journal={Cancer},
  year={2007},
  volume={110 5},
  pages={
          1149-61
        }
}
BACKGROUND Preclinical evidence suggests that anticoagulants, in particular the low-molecular-weight heparins (LMWH), exert an antitumor effect, whereas clinical trials have reported conflicting results. The authors conducted a comprehensive, systematic review and meta-analysis of the evidence from randomized controlled trials (RCTs), to evaluate the impact of anticoagulants on survival and safety in cancer patients without venous thromboembolism. METHODS A comprehensive systematic literature… CONTINUE READING
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