A meta‐analysis of the association between Caesarean section and childhood asthma

@article{Thavagnanam2008AMO,
  title={A meta‐analysis of the association between Caesarean section and childhood asthma},
  author={Surendran Thavagnanam and John Fleming and Ann Bromley and Michael D Shields and Chris R. Cardwell},
  journal={Clinical \& Experimental Allergy},
  year={2008},
  volume={38}
}
Background Children born by Caesarean section have modified intestinal bacterial colonization and consequently may have an increased risk of developing asthma under the hygiene hypothesis. The results of previous studies that have investigated the association between Caesarean section and asthma have been conflicting. 
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Caesarean section (CS) has been reported to increase the risk of asthma in offspring. This may be due to that infants delivered by CS are unexposed to vaginal flora, according to the ‘hygiene
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A large number of studies have shown an increased risk of childhood asthma for children born by Caesarean Section, and some suggest this risk may be higher than in children born without a Cesarean section.
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TLDR
An association between cesarean section and increased prevalence of childhood allergic diseases and these observations have been consistent in industrialized countries while evidence from developing countries is limited.
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TLDR
To provide evidence on the association between caesarean section and allergic manifestations in an unselected child population, a large sample of children from around the world were selected for research.
Delivery mode and the incidence of atopic sensitization and food allergy in a Finnish child population
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  • 2021
Caesarean section (CS) has been associated with an increased risk of subsequent atopic diseases, particularly asthma and respiratory allergies, but controversial findings have also been reported. Our
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TLDR
Evidence of a correlation between asthma, conception via in vitro fertilization (IVF) and delivery through Caesarean section (C‐section) is inconclusive.
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TLDR
To investigate the association between delivery by caesarean section and risk of childhood cancer, a large number of women were given a Caesareans during pregnancy to reduce the chance of developing childhood cancer.
Forceps birth delivery, allergic sensitisation and asthma: a population‐based cohort study
  • R. Hancox, C. Landhuis, M. Sears
  • Medicine, Biology
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
  • 2013
Studies indicate an increased risk of allergies among children born by caesarean section, possibly because immune development is altered by avoiding exposure to maternal vaginal flora. It is unknown
Time to consider the risks of caesarean delivery for long term child health
TLDR
The evidence linking caesarean delivery with childhood chronic disease and guidelines on delivery should be reviewed with these risks in mind are examined.
Atopic dermatitis is associated with Caesarean sections in Korean adolescents, but asthma is not
TLDR
The relationship between mode of delivery and atopic dermatitis and asthma in Korean adolescents and research has rarely been conducted in Asian countries such as South Korea.
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