A menstrual cycle pattern for cytokine levels exists in HIV-positive women: implication for HIV vaginal and plasma shedding.

@article{AlHarthi2001AMC,
  title={A menstrual cycle pattern for cytokine levels exists in HIV-positive women: implication for HIV vaginal and plasma shedding.},
  author={Lena Al-Harthi and Andrea A Kovacs and Robert W. Coombs and Patricia S Reichelderfer and David G. Wright and Mardge H. Cohen and Jonathan B. Cohn and Susan Cu-Uvin and Heather Watts and Sharon R. Lewis and Suzanne K. Beckner and Alan L. Landay},
  journal={AIDS},
  year={2001},
  volume={15 12},
  pages={1535-43}
}
OBJECTIVES To evaluate the effect of the menstrual cycle in HIV-positive women on plasma and genital cytokine levels, interrelationships between vaginal and plasma cytokines, CD4 and CD8 T cell fluctuations, and genital and plasma viral loads. METHODS Plasma and cervicovaginal lavage specimens were collected from 55 HIV-positive women with CD4 cell counts < 350 cells/microl during phases of the menstrual cycle. Samples were assayed for IL-1beta, IL-6, IL-4, IL-8, IL-10, TGFbeta, TNFalpha… CONTINUE READING

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