A memory retrieval-extinction procedure to prevent drug craving and relapse.

Abstract

Drug use and relapse involve learned associations between drug-associated environmental cues and drug effects. Extinction procedures in the clinic can suppress conditioned responses to drug cues, but the extinguished responses typically reemerge after exposure to the drug itself (reinstatement), the drug-associated environment (renewal), or the passage of… (More)
DOI: 10.1126/science.1215070

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Cite this paper

@article{Xue2012AMR, title={A memory retrieval-extinction procedure to prevent drug craving and relapse.}, author={Yan-xue Xue and Yi-xiao Luo and Ping Wu and Hai-shui Shi and Li-fen Xue and Chen Chen and Wei-li Zhu and Zeng-bo Ding and Yan-Ping Bao and Jie Shi and David H. Epstein and Yavin Shaham and Lin Lu}, journal={Science}, year={2012}, volume={336 6078}, pages={241-5} }