A meiotic gene conversion gradient opposite to the direction of transcription

@article{Malone1992AMG,
  title={A meiotic gene conversion gradient opposite to the direction of transcription},
  author={Robert E. Malone and Steven A. Bullard and Steven Lundquist and Sangkyu Kim and Trudee A. Tarkowski},
  journal={Nature},
  year={1992},
  volume={359},
  pages={154-155}
}
GENETIC recombination involves classical crossing-over and gene conversion (aberrant segregation). In fungi that produce an ascus containing four spores, a gene conversion event is manifested as 3:1 or 1:3 (or more rarely 4:0 or 0:4) segregations, in contrast to the normal mendelian 2:2 segregation1,2. Polarity is one of the properties of gene conversion; in almost all cases the frequency of conversion exhibits a gradient across the gene monitored1. The frequency of conversion is usually… CONTINUE READING

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