A mechanosensitive channel protein and its gene in E. coli.

  title={A mechanosensitive channel protein and its gene in E. coli.},
  author={Paul Blount and Sergei Sukharev and Ching Kung},
  journal={Gravitational and space biology bulletin : publication of the American Society for Gravitational and Space Biology},
  volume={10 2},
Receptor molecules that respond directly to gravity, touch, vibration, or osmotic pressure are inferred from their functions but not yet characterized as isolated proteins or products of cloned genes. These receptors are often in low abundance and in animal and plant tissues that are inaccessible, thus making biochemical analysis difficult. Yet, the application of the sensitive patch-clamp technique to measure transmembrane currents has demonstrated the ubiquity of ion channels whose opening is… CONTINUE READING