A mechanochemical approach to deracemization.

@article{Wiggins2012AMA,
  title={A mechanochemical approach to deracemization.},
  author={Kelly M. Wiggins and Christopher W. Bielawski},
  journal={Angewandte Chemie},
  year={2012},
  volume={51 7},
  pages={1640-3}
}
The synthesis and isolation of enantiopure compounds remains an important challenge for many applications in medicinal, materials, and synthetic chemistry. In general, chiral molecules of high enantiopurity are prepared by asymmetric synthesis or the resolution of their respective racemates. The latter approach is more common but can be tedious, and the yields of isolated products are inherently restricted to, at best, 50%. An ideal solution to this problem is to reconfigure the stereochemistry… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-2 of 2 references

Chirality from Dynamic Kinetic Resolution

  • H. Pellissier
  • RSC Publishing, Cambridge
  • 2011
1 Excerpt

Stereochemistry of Organic Compounds (Ed: L

  • E. L. Eliel, S. H. Wilen
  • N. Mander), Wiley, New York
  • 1994
1 Excerpt

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