A mechanistic basis for potent, glycoprotein B-directed gammaherpesvirus neutralization

Abstract

Glycoprotein B (gB) is a conserved, essential component of gammaherpes virions and so potentially vulnerable to neutralization. However, few good gB-specific neutralizing antibodies have been identified. Here, we show that murid herpesvirus 4 is strongly neutralized by mAbs that recognize an epitope close to one of the gB fusion loops. Antibody binding did… (More)
DOI: 10.1099/vir.0.032177-0

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@inproceedings{Glauser2011AMB, title={A mechanistic basis for potent, glycoprotein B-directed gammaherpesvirus neutralization}, author={Daniel L. Glauser and Anne-Sophie Kratz and Laurent Gillet and Philip G Stevenson}, booktitle={The Journal of general virology}, year={2011} }