A mechanism for morphogen-controlled domain growth.

  title={A mechanism for morphogen-controlled domain growth.},
  author={Ruth E. Baker and Philip K. Maini},
  journal={Journal of mathematical biology},
  volume={54 5},
Many developmental systems are organised via the action of graded distributions of morphogens. In the Drosophila wing disc, for example, recent experimental evidence has shown that graded expression of the morphogen Dpp controls cell proliferation and hence disc growth. Our goal is to explore a simple model for regulation of wing growth via the Dpp gradient: we use a system of reaction-diffusion equations to model the dynamics of Dpp and its receptor Tkv, with advection arising as a result of… CONTINUE READING