A mechanism-based combination therapy reduces local tumor growth and metastasis in an orthotopic model of prostate cancer.

Abstract

Therapy-induced stimulation of angiogenic molecules can promote tumor angiogenesis leading to enhanced tumor growth and cancer metastasis. Several standard and emerging therapies, such as radiation and photodynamic therapy (PDT), can induce angiogenic molecules, thus limiting their effectiveness. PDT is approved for the treatment of several cancers; however… (More)

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Cite this paper

@article{Kosharskyy2006AMC, title={A mechanism-based combination therapy reduces local tumor growth and metastasis in an orthotopic model of prostate cancer.}, author={Boleslav Kosharskyy and Nicolas Solban and Sung K. Chang and Imran A. Rizvi and Yuchiao Chang and T. Karaoglu Hasan}, journal={Cancer research}, year={2006}, volume={66 22}, pages={10953-8} }