A mathematical model of radiation carcinogenesis with induction of genomic instability and cell death.

Abstract

We developed a mathematical model of carcinogenesis that incorporates genomic instability, a feature characterized by long-term destabilization of the genome in irradiated cells that leads to an increase in cancer risk in the exposed individuals at the cancer-prone age. This model also considers the induction of cell death, another important effect of… (More)

Topics

Cite this paper

@article{Ohtaki2001AMM, title={A mathematical model of radiation carcinogenesis with induction of genomic instability and cell death.}, author={Megu Ohtaki and Ohtsura Niwa}, journal={Radiation research}, year={2001}, volume={156 5 Pt 2}, pages={672-7} }