A mathematical model of neutrophil production and control in normal man.

@article{Rubinow1975AMM,
  title={A mathematical model of neutrophil production and control in normal man.},
  author={S. I. Rubinow and Jonathan L Lebowitz},
  journal={Journal of mathematical biology},
  year={1975},
  volume={1 3},
  pages={187-225}
}
A comprehensive mathematical model of neutrophil production in normal man is presented. The model incorporates three control elements which regulate homeostatically the rates of release of marrow cells to proliferation, maturation, and to the blood. The steady state properties of the model are demonstrated analytically. The basic equations of the model, which are nonlinear, have been integrated numerically. The solutions so obtained display graphically the dynamical response of the system to… CONTINUE READING

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