A mathematical model of O2 transport in the rat outer medulla. II. Impact of outer medullary architecture.

@article{Chen2009AMM,
  title={A mathematical model of O2 transport in the rat outer medulla. II. Impact of outer medullary architecture.},
  author={Jing Chen and Aur{\'e}lie Edwards and A. T. Layton},
  journal={American journal of physiology. Renal physiology},
  year={2009},
  volume={297 2},
  pages={F537-48}
}
we extended the region-based mathematical model of the urine-concentrating mechanism in the rat outer medulla (OM) developed by Layton and Layton (Am J Physiol Renal Physiol 289: F1346-F1366, 2005) to examine the impact of the complex structural organization of the OM on O(2) transport and distribution. In the present study, we investigated the sensitivity of predicted Po(2) profiles to several parameters that characterize the degree of OM regionalization, boundary conditions, structural… CONTINUE READING

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A mathematical model of the inner medullary collecting duct of the rat: pathways for Na and K transport

  • AM Weinstein
  • Am J Physiol Renal Physiol 274:
  • 1998
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