• Corpus ID: 119460507

A mathematical approach to aspects of LET, micro- and nano-dosimetry in radiation therapy with photons and charged particles

  title={A mathematical approach to aspects of LET, micro- and nano-dosimetry in radiation therapy with photons and charged particles},
  author={Waldemar Ulmer},
  journal={arXiv: Medical Physics},
  • W. Ulmer
  • Published 30 November 2017
  • Physics
  • arXiv: Medical Physics
The radiation effects induced by Co60 serve as a reference system for the consideration of LET and RBE in normal and tumor tissue dose-effect relations are usually handled by the linear-quadratic model (LQ). This approximation excellently works up to the shoulder domain. In particle therapy we have strictly differ between RBE in the initial plateau and environment of the Bragg peak. Thus for protons LET and RBE of the initial plateau agree with Co60, whereas in the Bragg peak domain both… 



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