A maternally inherited superantigen encoded by a mammary tumour virus

@article{Marrack1991AMI,
  title={A maternally inherited superantigen encoded by a mammary tumour virus},
  author={Philippa C. Marrack and Elenora Kushnir and John W Kappler},
  journal={Nature},
  year={1991},
  volume={349},
  pages={524-526}
}
  • Philippa C. Marrack, Elenora Kushnir, John W Kappler
  • Published 1991
  • Biology, Medicine
  • Nature
  • A COLLECTION of superantigens, molecules which in combination with class II major histocompatibility complex (MHC) engage T cells bearing particular Vβ chains as part of their αβ receptors, have recently been described1,2. The mouse self superantigen, Mls-la, for example, in conjunction with many MHC class II proteins, engages mouse T cells bearing Vβ6,7,8.1 and 9, almost regardless of the sequences of the other variable components of the receptors on the T cells3–5. Two types of superantigen… CONTINUE READING

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