A master relation defines the nonlinear viscoelasticity of single fibroblasts.

  title={A master relation defines the nonlinear viscoelasticity of single fibroblasts.},
  author={Pablo Fern{\'a}ndez and Pramod A. Pullarkat and Albrecht Ott},
  journal={Biophysical journal},
  volume={90 10},
Cell mechanical functions such as locomotion, contraction, and division are controlled by the cytoskeleton, a dynamic biopolymer network whose mechanical properties remain poorly understood. We perform single-cell uniaxial stretching experiments on 3T3 fibroblasts. By superimposing small amplitude oscillations on a mechanically prestressed cell, we find a transition from linear viscoelastic behavior to power law stress stiffening. Data from different cells over several stress decades can be… CONTINUE READING
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