A marker for hypoxic cells in tumours with potential clinical applicability.

@article{Chapman1981AMF,
  title={A marker for hypoxic cells in tumours with potential clinical applicability.},
  author={J. D. Chapman and Allan J. Franko and J. Sharplin},
  journal={British Journal of Cancer},
  year={1981},
  volume={43},
  pages={546 - 550}
}
CGRAY et al. (1953) suggested that the oxygen concentration in tumour cells might influence the curability of some human cancers by ionizing radiation. Recent clinical investigations using hyp-oxic cell radiosensitizers (Urtasun et al., 1976), hyperbaric oxygen (Henk & Smith, 1977) and pretherapy transfusion of anaemic patients (Bush et al., 1978) con-firnm the postulate that lhypoxia does influence the radiocurability of some tumours. Although the oxygenation status of tumours is considered to… CONTINUE READING

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Delineation techniques of tumor hypoxia volume with 18F-FMISO PET imaging

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