A mammary gland EST showing linkage disequilibrium to a milk production QTL on bovine Chromosome 14

@article{Looft2001AMG,
  title={A mammary gland EST showing linkage disequilibrium to a milk production QTL on bovine Chromosome 14},
  author={Christian Looft and Norbert Reinsch and Christina Karall-Albrecht and Sven Paul and Maren Brink and Hauke Thomsen and Gudrun A. Brockmann and Christa Kuehn and Manfred Schwerin and Ernst Kalm},
  journal={Mammalian Genome},
  year={2001},
  volume={12},
  pages={646-650}
}
As part of a genome scan, ESTs derived from mammary gland tissue of a lactating cow were used as candidate genes for quantitative trait loci (QTL), affecting milk production traits. Resource families were genotyped with 247 microsatellite markers and 4 polymorphic ESTs. It was shown by linkage analysis that one of these ESTs, KIEL_E8, mapped to the centromeric region of bovine Chromosome (Chr) 14. Regression analysis revealed the presence of a QTL, with significant effect on milk production, in… CONTINUE READING
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