A major role for thalamocortical afferents in serotonergic hallucinogen receptor function in the rat neocortex

@article{Marek2001AMR,
  title={A major role for thalamocortical afferents in serotonergic hallucinogen receptor function in the rat neocortex},
  author={G. Marek and R. Wright and J. Gewirtz and D. Schoepp},
  journal={Neuroscience},
  year={2001},
  volume={105},
  pages={379-392}
}
Activation of 5-hydroxytryptamine(2A) (5-HT(2A)) receptors by hallucinogenic drugs is thought to mediate many psychotomimetic effects including changes in affect, cognition and perception. Conversely, blockade of 5-HT(2A) receptors may mediate therapeutic effects of many atypical antidepressant and antipsychotic drugs. The purpose of the present study was to determine the source of subcortical glutamatergic afferents, which would project widely throughout the anterior-posterior axis of the rat… Expand
145 Citations
Electrophysiology of Serotonin Receptors
  • 10
Presynaptic serotonin 2A receptors modulate thalamocortical plasticity and associative learning
  • 48
  • PDF
Effects of Hallucinogens on Neuronal Activity.
  • 5
In vivo modulation of the activity of pyramidal neurons in the rat medial prefrontal cortex by 5-HT2A receptors: relationship to thalamocortical afferents.
  • 186
  • Highly Influenced
  • PDF
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 47 REFERENCES
Physiological antagonism between 5-hydroxytryptamine(2A) and group II metabotropic glutamate receptors in prefrontal cortex.
  • 252
  • PDF
Comparative localization of serotonin1A, 1C, and 2 receptor subtype mRNAs in rat brain
  • 557
Neuroanatomical patterns of the mu, delta, and kappa opioid receptors of rat brain as determined by quantitative in vitro autoradiography.
  • A. Tempel, R. Zukin
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 1987
  • 352
  • PDF
...
1
2
3
4
5
...