A major role for nonenzymatic antioxidant processes in the radioresistance of Halobacterium salinarum.

@article{Robinson2011AMR,
  title={A major role for nonenzymatic antioxidant processes in the radioresistance of Halobacterium salinarum.},
  author={Courtney Kathryn Robinson and Kim Webb and Amardeep Kaur and Pawel Jaruga and Miral Dizdaroğlu and Nitin S. Baliga and Allen Place and Jocelyne DiRuggiero},
  journal={Journal of bacteriology},
  year={2011},
  volume={193 7},
  pages={1653-62}
}
Oxidative stress occurs when the generation of reactive oxygen species (ROS) exceeds the capacity of the cell's endogenous systems to neutralize them. Our analyses of the cellular damage and oxidative stress responses of the archaeon Halobacterium salinarum exposed to ionizing radiation (IR) revealed a critical role played by nonenzymatic antioxidant processes in the resistance of H. salinarum to IR. ROS-scavenging enzymes were essential for resistance to chemical oxidants, yet those enzymes… CONTINUE READING
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