A major phosphoprotein of the endoplasmic reticulum is protein disulfide isomerase.


One of the effects of ATP in the endoplasmic reticulum is to induce the phosphorylation of several proteins among which a 57-kDa protein (pp57) prevails in our labeling conditions. We provide evidence that pp57 is protein disulfide isomerase (PDI), an abundant ubiquitous protein of the endoplasmic reticulum involved in various important cellular functions… (More)