A major locus conferring susceptibility to infection by Streptococcus pneumoniae in mice

Abstract

We have studied the genetics of susceptibility to infection by Streptococcus pneumoniae in mice. Linkage analysis of the F2 generation from a cross between resistant BALB/cO1aHsd and susceptible CBA/CaO1aHsd strains allowed us to map a major locus controlling the development of bacteremia and survival after intranasal infection.

DOI: 10.1007/s00335-002-2261-9

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@article{Denny2003AML, title={A major locus conferring susceptibility to infection by Streptococcus pneumoniae in mice}, author={Paul Denny and Elaine Hopes and Neill A Gingles and Karl W. Broman and William L. McPheat and John Morten and Janet Leath Alexander and P. W. Andrew and Steve D. M. Brown}, journal={Mammalian Genome}, year={2003}, volume={14}, pages={448-453} }